Research Articles
Molecular Scissors: How an Enzyme's Radical Move Builds the Stuff of Life
Discover how ribonucleoside triphosphate reductase uses a radical mechanism to convert RNA components into DNA building blocks through concerted carbon-cobalt bond homolysis.
Build Your Own Enzyme: Engineering Nature's Molecular Machinery
Discover how scientists are designing biological catalysts from scratch to perform valuable chemical transformations like the Diels-Alder reaction.
Unveiling Enzyme Secrets: How a Molecular Snapshot Revolutionized Catalysis
Discover how scientists captured a pre-transition-state mimic of adenosine deaminase, revealing the molecular mechanisms of enzymatic catalysis and advancing our understanding of immune system function.
Unveiling Nature's Molecular Masterpiece: The Atomic Structure of a Steroid-Transforming Enzyme
Explore the groundbreaking discovery of the solution structure of Delta 5-3-ketosteroid isomerase complexed with 19-nortestosterone hemisuccinate and its implications for enzymology.